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DBT

Basics

Aliases:
This biomarker is also known as:
  • BCKAD E2 Subunit,
  • Dihydrolipoamide Branched Chain Transacylase (E2 Component Of Branched Chain Keto Acid Dehydrogenase Complex; Maple Syrup Urine Disease),
  • Lipoamide Acyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex, Mitochondrial,
  • Mitochondrial Branched Chain Alpha-Keto Acid Dehydrogenase Transacylase Subunit (E2b),
  • E2 Component Of Branched Chain Alpha-Keto Acid Dehydrogenase Complex,
  • Dihydrolipoamide Branched Chain Transacylase E2,
  • BCKAD-E2,
  • EC 2.3.1.168,
  • Lipoamide Acyltransferase Component Of Mitochondrial Branched-Chain Alpha-Keto Acid Dehydrogenase Complex,
  • BCKADE2,
  • Dihydrolipoyl Transacylase,
  • E2,
  • BCATE2,
  • Dihydrolipoamide Branched Chain Transacylase,
  • E2B,
  • Branched Chain Acyltransferase, E2 Component,
  • Dihydrolipoamide Acetyltransferase Component Of Branched-Chain Alpha-Keto Acid Dehydrogenase Complex,
  • Branched-Chain Alpha-Keto Acid Dehydrogenase Complex Component E2,
  • Dihydrolipoyllysine-Residue (2-Methylpropanoyl)Transferase,

View in BioMuta

Description…

From NCBI Gene: The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: DBT

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement