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CSNK1E

Basics

Aliases:
This biomarker is also known as:
  • EC 2.7.11,
  • EC 2.7.11.1,
  • CKIe,
  • CKI-epsilon,
  • CKIepsilon,
  • CKIE,
  • casein kinase 1, epsilon,
  • casein kinase I isoform epsilon,
  • HCKIE,

View in BioMuta

Description…

CSNK1E is a serine/threonine protein kinase and a member of the casein kinase I protein family. Casein kinases are characterized by their preferential utilization of acidic proteins such as caseins as substrates. Members of the casein kinase I protein family have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair, and have been shown to phosphorylate a variety of proteins, including itself. CSNK1E is a monomeric cytoplasmic protein. CSNK1E has been shown to phosphorylate period, a circadian rhythm protein, and as such is a central component of the circadian clock. CSNK1E may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Two transcript variants encoding the same protein have been found for this gene.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: CSNK1E

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.