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CEACAM5

Basics

Aliases:
This biomarker is also known as:
  • Carcinoembryonic antigen,
  • carcinoembryonic antigen-related cell adhesion molecule 5,
  • CEA,
  • CD_antigen=CD66e,
  • Meconium antigen 100,
  • CD66e,
  • DKFZp781M2392,

View in BioMuta

Description…

CEA is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. It is a receptor for E.coli Dr adhesins.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: CEACAM5

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Lung

Attributes

Phase: Two
QA State: Under Review

Overview

Performance Comment

Ovary

Attributes

Phase: Two
QA State: Under Review

Overview

CEACAM5 is a member of the carcinoembryonic antigen (CEA) family. The carcinoembryonic proteins are found normally in the blood of a fetus. The CEA proteins are also found in the blood of some people who have certain types of tumors, such as colorectal, pancreas, breast, ovary, or lung. CEA levels are not usually elevated in early cancer, and in some cancers are not elevated at all.

Performance Comment

Despite many promising new markers for ovarian cancer, CA125 remains the single best biomarker in the phase II and phase III specimens tested in this study.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 11/20/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.