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CCL5

Basics

Aliases:
This biomarker is also known as:
  • TCP228,
  • T-cell-specific protein RANTES,
  • regulated upon activation, normally T-expressed, and presumably secreted,
  • small inducible cytokine A5 (RANTES),
  • EoCP,
  • t cell-specific protein P228,
  • small inducible cytokine subfamily A (Cys-Cys), member 5,
  • beta-chemokine RANTES,
  • Eosinophil chemotactic cytokine,
  • D17S136E,
  • RANTES,
  • Small-inducible cytokine A5,
  • SISd,
  • eoCP,
  • C-C motif chemokine 5,
  • T-cell specific protein p288,
  • chemokine (C-C motif) ligand 5,
  • T cell-specific protein P228,
  • SIS-delta,
  • MGC17164,
  • SCYA5,
  • small-inducible cytokine A5,
  • eosinophil chemotactic cytokine,

View in BioMuta

Description…

CCL5 (RANTES) is a chemokine, a subfamily of cytokines. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. CCL5 is a chemoattractant for blood monocytes, memory T-helper cells and eosinophils and causes the release of histamine from basophils and activates eosinophils. There are several transcript variants that encode different isoforms.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: CCL5

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

The chemokine CCL5 (RANTES), a major monocyte chemoattractant expressed by breast tumor cells, has been implicated in the progression of breast cancer.

Performance Comment

CCL5 (RANTES) was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement