Aliases:This biomarker is also known as:
- small-inducible cytokine A5,
- t cell-specific protein P228,
- eosinophil chemotactic cytokine,
- chemokine (C-C motif) ligand 5,
- Small-inducible cytokine A5,
- beta-chemokine RANTES,
- C-C motif chemokine 5,
- small inducible cytokine subfamily A (Cys-Cys), member 5,
- T-cell specific protein p288,
- regulated upon activation, normally T-expressed, and presumably secreted,
- Eosinophil chemotactic cytokine,
- T cell-specific protein P228,
- T-cell-specific protein RANTES,
- small inducible cytokine A5 (RANTES),
CCL5 (RANTES) is a chemokine, a subfamily of cytokines. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. CCL5 is a chemoattractant for blood monocytes, memory T-helper cells and eosinophils and causes the release of histamine from basophils and activates eosinophils. There are several transcript variants that encode different isoforms.
There are no datasets associated with this biomarker.
The following organs have data associated with this biomarker…
|QA State:||Under Review|
The chemokine CCL5 (RANTES), a major monocyte chemoattractant expressed by breast tumor cells, has been implicated in the progression of breast cancer.
CCL5 (RANTES) was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.