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This biomarker is also known as:
  • eosinophil chemotactic cytokine,
  • small inducible cytokine subfamily A (Cys-Cys), member 5,
  • T cell-specific protein P228,
  • T-cell-specific protein RANTES,
  • SCYA5,
  • regulated upon activation, normally T-expressed, and presumably secreted,
  • chemokine (C-C motif) ligand 5,
  • TCP228,
  • D17S136E,
  • beta-chemokine RANTES,
  • SIS-delta,
  • MGC17164,
  • EoCP,
  • small inducible cytokine A5 (RANTES),
  • C-C motif chemokine 5,
  • Eosinophil chemotactic cytokine,
  • T-cell specific protein p288,
  • Small-inducible cytokine A5,
  • small-inducible cytokine A5,
  • eoCP,
  • SISd,
  • t cell-specific protein P228,

View in BioMuta


CCL5 (RANTES) is a chemokine, a subfamily of cytokines. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. CCL5 is a chemoattractant for blood monocytes, memory T-helper cells and eosinophils and causes the release of histamine from basophils and activates eosinophils. There are several transcript variants that encode different isoforms.


QA State: Curated
Type: Protein
Short Name:


There are no datasets associated with this biomarker.


The following organs have data associated with this biomarker…



Phase: Two
QA State: Under Review


The chemokine CCL5 (RANTES), a major monocyte chemoattractant expressed by breast tumor cells, has been implicated in the progression of breast cancer.

Performance Comment

CCL5 (RANTES) was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.


This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.