Skip to content. | Skip to navigation

National Cancer Institute U.S. National Institutes of Health www.cancer.gov

Navigation

Personal tools

You are here: Home / Biomarkers / BPIFA1

BPIFA1

Basics

Aliases:
This biomarker is also known as:
  • BPI Fold-Containing Family A Member 1,
  • Palate, Lung And Nasal Epithelium Carcinoma Associated,
  • BPI Fold Containing Family A, Member 1,
  • Tracheal Epithelium Enriched Protein,
  • Tracheal Epithelium-Enriched Protein,
  • Secretory Protein In Upper Respiratory Tracts,
  • SPLUNC1,
  • BA49G10.5,
  • Palate Lung And Nasal Epithelium Clone Protein,
  • LUNX,
  • SPURT,
  • Ligand-Binding Protein RYA3,
  • Nasopharyngeal Carcinoma-Related Protein,
  • NASG,
  • Lung-Specific Protein X,
  • PLUNC,
  • Von Ebner Protein Hl,
  • Protein Plunc,
  • Palate, Lung And Nasal Epithelium Associated,

View in BioMuta

Description…

The BPIFA1 gene was formerly known as PLUNC. This human gene is the homolog of murine Plunc, and shows the same expression pattern as murine Plunc. Both are expressed in the upper airways and nasopharyngeal regions. Human BPIFA1 may be involved in the airway inflammatory response after exposure to irritants and may be associated with tumor progression. BPIFA1 may also play a role in innate immune responses of the upper airways. And it may serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but only three full length variants have been isolated.

Attributes

QA State: Under Review
Type: Gene
Short Name:
HGNC Name: BPIFA1

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 12/02/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.