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BMX

Basics

Aliases:
This biomarker is also known as:
  • EC 2.7.10,
  • Epithelial and endothelial tyrosine kinase,
  • cytoplasmic tyrosine-protein kinase BMX,
  • EC 2.7.10.2,
  • Etk/Bmx cytosolic tyrosine kinase,
  • NTK38,
  • NTK38 tyrosine kinase,
  • PSCTK2,
  • PSCTK3,
  • BMX non-receptor tyrosine kinase,
  • ETK,
  • Bone marrow tyrosine kinase gene in chromosome X protein,

View in BioMuta

Description…

BMX, or BMX non-receptor tyrosine kinase, belongs to the Tec kinase family. BMX, a non-receptor tyrosine kinase, plays a central but diverse modulatory role in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. The BMX protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: BMX

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.
Announcement 09/14/2014

Thank you to everyone who helped make the 9th EDRN Scientific Workshop a success. We look forward to seeing everyone at the 28th EDRN Steering Committee Meeting from March 31-April 2, 2015, in Atlanta, GA.