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BLVRB

Basics

Aliases:
This biomarker is also known as:
  • BVRB,
  • Biliverdin-IX beta-reductase,
  • short chain dehydrogenase/reductase family 43U, member 1,
  • SDR43U1,
  • GHBP,
  • Green heme-binding protein,
  • Flavin reductase,
  • NADPH-flavin reductase,
  • BVR-B,
  • NADPH-dependent diaphorase,
  • biliverdin reductase B (flavin reductase (NADPH)),
  • FLR,
  • Biliverdin reductase B,
  • FR,
  • MGC117413,

View in BioMuta

Description…

BLVRB, a cytoplasmic protein, is a broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and pyrroloquinoline quinone. It contributes to heme catabolism and metabolizes linear tetrapyrroles. BLVRB can also reduce the complexed Fe3+ iron to Fe2+ in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin. BLVRB is predominantly expressed in liver and erythrocytes, and at lower levels in heart, lung, adrenal gland and cerebrum.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: BLVRB

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 Steering Committee Meeting

The next EDRN Steering Committee Meeting will take place March 31st through April 2nd, 2015, in Atlanta, Georgia.

Announcement 02/12/2015

Please register for the 29th EDRN Steering Committee Meeting in Atlanta, GA from March 31-April 2, 2015. The registration page has information about booking hotel rooms and a draft agenda of the meeting.

Announcement