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APCS

Basics

Aliases:
This biomarker is also known as:
  • Serum amyloid P-component,
  • 9.5S alpha-1-glycoprotein,
  • amyloid P component, serum,
  • pentaxin-related,
  • PTX2,
  • SAP,
  • MGC88159,

View in BioMuta

Description…

APCS, a secreted glycoprotein found in serum and urine, interacts with DNA and histones and may scavenge nuclear material released from damaged circulating cells. It is thought to control the degradation of chromatin and has been demonstrated to bind to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. APCS may also function as a calcium-dependent lectin. APCS is a member of the pentaxin family of proteins, which characteristically bind two calcium ions per subunit and have a a discoid arrangement of 5 non-covalently bound subunits.

Attributes

QA State: Under Review
Type: Protein
Short Name:
HGNC Name: APCS

Datasets

There are no datasets associated with this biomarker.

Organs

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Publications

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Resources

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

2015 EDRN PI Orientation

The New and Continuing EDRN Principal Investigator Orientation will take place October 15–16, 2015 in Bethesda, Maryland.

Announcement 04/08/2015

Thank you to everyone who made the 29th EDRN Steering Committee Meeting a success. The orientation for new and continuing EDRN PIs will be held October 15-16, 2015 on the NCI campus. More information will be available later this summer.

Announcement