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ADH5

Basics

Aliases:
This biomarker is also known as:
  • GSNOR,
  • alcohol dehydrogenase (class III), chi polypeptide,
  • FALDH,
  • ADHX,
  • FDH,
  • alcohol dehydrogenase class chi chain,
  • glutathione-dependent formaldehyde dehydrogenase,
  • Glutathione-dependent formaldehyde dehydrogenase,
  • alcohol dehydrogenase 5 (class III), chi polypeptide,
  • alcohol dehydrogenase class-III,
  • formaldehyde dehydrogenase,
  • GSH-FDH,
  • Alcohol dehydrogenase 5,
  • S-(hydroxymethyl)glutathione dehydrogenase,
  • EC 1.1.1.1,EC 1.1.1.-,EC 1.1.1.284,
  • Alcohol dehydrogenase class chi chain,
  • Alcohol dehydrogenase class-III,
  • alcohol dehydrogenase class-3,
  • ADH-3,

View in BioMuta

Description…

ADH5 is a member of the alcohol dehydrogenase family. This protein forms a homodimer. ADH5 is ineffective in oxidizing ethanol, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. There are several non-transcribed pseuodogenes related to this gene.

Attributes

QA State: Curated
Type: Protein
Short Name:
HGNC Name: ADH5

Datasets

There are no datasets associated with this biomarker.

Organs

The following organs have data associated with this biomarker…

Breast

Attributes

Phase: Two
QA State: Under Review

Overview

No additional breast data available.

Performance Comment

ADH5 was one of numerous potential early detection biomarkers specific to triple-negative breast cancer in multiple pathways identified.

Studies

This biomarker is currently being annotated or is under review. You must be logged in or do not have permission to view any additional information. Contact Heather Kincaid at heather.kincaid@jpl.nasa.gov if you should have access to this biomarker.

Announcement 11/20/2014

New Round of EDRN FOAs

The RFAs for EDRN have been released:
- Biomarker Developmental Laboratories (U01),
- Clinical Validation Centers (U01),
- Biomarker Reference Laboratories (U24),
- Data Management and Coordinating Center (U24).

EDRN Renewal flyer NOTE-New receipt deadline for applications submitted for all EDRN FOAs is January 20, 2015, by 5:00 PM local time of applicant organization.

There will be a Pre-Application webinar to discuss each of the four individual EDRN FOAs on Tuesday, December 2nd, 2014, from 1pm-5pm (Eastern). Potential applicants interested in participating in the webinar should send a message to Dr. Sharmistha Ghosh (ghoshjanjigias@mail.nih.gov) no later than 5:00 p.m. (EST) November 21, 2014. Please mention the FOA of interest in the subject line.

Announcement 10/07/2014

EDRN Patient Advocates will host an EDRN Advocacy Educational Webinar, Biomarkers for Prostate Cancer Detection and Monitoring, on Monday, January 12th, 2015, at 1 p.m. EDT / 10 a.m. PDT. Registration is not required for this. Please click for more information.