Aliases:This biomarker is also known as:
- Elastically scattering light fingerprinting,
Identification of preneoplastic changes in histologically normal epithelium (the "field effect") could provide a powerful screening tool for colorectal cancer. A new generation of optical technology, 4-dimensional elastic light-scattering fingerprinting (4D-ELF), enables probing of the nanoscale/microscale architecture of living cells. Initial studies show that probing the nanoscale cellular architecture with 4D-ELF detect the earliest stages of colon carcinogenesis in the rat model of colon carcinogenesis. Future studies are necessary to explore the clinical applicability of this technology and elucidate the biological determinants of these microarchitectural changes.
|QA State:||Under Review|
There are no datasets associated with this biomarker.